The woolly mammoth has not walked the Earth for 4,000 years. Killed off at the end of the last ice age, it’s part of a group of extinct species that continue to inspire biologists, and one that US biotech startup Colossal – the self-proclaimed “de-extinction company” – has set its sights on reviving.

Colossal’s audacious plan involves creating a genetically engineered Asian elephant-mammoth hybrid, then introducing it to the Arctic tundra. The project has received millions of dollars in backing and has been met with both curiosity and a degree of scientific skepticism.

For Colossal to succeed, it must overcome many hurdles, including crafting the animal’s genetic sequence, successfully fertilizing an egg, and growing it to term. But birth is only the beginning. How these animals will live in the wild is a question that will take a lifetime or more to answer, and Colossal is turning to other animals for help – including a group of elephants in Botswana.

The startup has entered a collaboration with Elephant Havens, a wildlife foundation based in the Okavango Delta that cares for orphaned elephants.

Founded in 2017, Elephant Havens will partner with Colossal on an extensive data-gathering operation, using artificial intelligence (AI) to analyze the animals’ behavior and pair it with genomic data on each elephant. “We’ll be able to mix the art of the elephant handlers with the science of today,” argues Matt James, chief animal officer at Colossal.

The findings, the organizations hope, could provide a blueprint for releasing the elephants into the wild and mammoth hybrids to the tundra.

A new system for elephant monitoring

Human-wildlife conflict is the leading cause of elephant orphans in Botswana, says Elephant Havens founder Debra Stevens.

Elephant Havens co-founder Debra Stevens said, “nine times out of 10,” elephants in Botswana are orphaned due to human-wildlife conflict. Many of the foundation’s orphans were made so because of fires. “The herd will separate, and they lose their babies,” she explained. “That’s always tragic to witness, because they desperately want to find their mothers – so we try and become mothers for them.”

Reintroducing elephants to the wild is difficult. Social hierarchies are complex and introducing an orphan to a wild herd is not a good idea, says Stevens. But without a family unit, orphaned elephants have been reported to perish from grief. Even when elephants are reintroduced as a group, they don’t always revel in their independence, she adds, and have a habit of finding their way back to the place they were raised in captivity.

Elephant Havens is engaged in a long-term reintroduction project, in which orphans are “soft released” into a 1,000-acre fenced site for five years, where they gradually learn to survive without human input.

Seven elephant youths including a matriarch and a male currently live in the soft release area, while seven younger elephants are cared for in an orphanage and will be moved to the enclosure at a later date. After five years in the enclosure, Elephant Havens will reintroduce these bonded herds into the wild, and monitor their progress for a decade.

Colossal Biosciences team at Elephant Havens in Botswana, Africa. From left to right: Steve Metzler, Matt James, Dr. Wendy Kiso.

Colossal is looking to harness the know-how of Elephant Havens’ experts and pair it with AI modeling and genetic data to learn more about the elephants.

“We’re looking at it from the perspective of how we would work with woolly mammoths in rewilding,” explained James.

“We have to look at motherless, loose family units. We’re going to build these family units, and then they’ll be raised alongside each other to create that first generation of mammoths. It’s a very similar situation to what Debra and the team in Botswana face when they receive orphans.”

James said that stationary cameras will record video, which will be analyzed by handlers and turned into data points to teach an AI to understand elephant social behaviors – leadership models, for example.

“There are a lot of people that have studied elephant behavior, but to put it into a system like this, that has never been done before,” James said.

“The more data you put into these systems, the stronger those correlations become, the more it understands elephant behavior,” he added.